Bioinformatics Platform Publications

Lautenschläger N, Schmidt K, Schiffer C, Wulff TF, Hahnke K, Finstermeier K, Mansour M, Elsholz AKW and Charpentier E (2024) Expanding the genetic toolbox for the obligate human pathogen Streptococcus pyogenes. Front. Bioeng. Biotechnol. https://doi.org/10.3389/fbioe.2024.1395659

Wulff TF, Hahnke K, Lécrivain A-L, Schmidt K, Ahmed-Begrich R, Finstermeier K and Charpentier E (2023) Dynamics of diversified A-to-I editing in Streptococcus pyogenes is governed by changes in mRNA stability (preprint). bioRxiv. https://doi.org/10.1101/2023.09.19.555891

Miao R, Jahn M, Shabestary K, Peltier G and Hudson EP (2023) CRISPR interference screens reveal growth–robustness tradeoffs in Synechocystis sp. PCC 6803 across growth conditions The Plant Cell, koad208. https://doi.org/10.1093/plcell/koad208  

Grätz L, Kowalski-Jahn M, Scharf MM, Kozielewicz P, Jahn M, Bous J, Lambert NA, Gloriam DE and Schulte G (2023) Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations Nat Commun, 14(1), 4573. https://doi.org/10.1038/s41467-023-40213-0    

Christensen S, Rämisch S and André I (2022) DnaK response to expression of protein mutants is dependent on translation rate and stability Commun Biol, 5(1), 597. https://doi.org/10.1038/s42003-022-03542-2  

Stelbrink B, Von Rintelen T, Richter K, Finstermeier K, Frahnert S, Cracraft J and Hofreiter M (2022) Insights into the geographical origin and phylogeographical patterns of Paradisaea birds-of-paradise Zoological Journal of the Linnean Society, 196(4), 1394–1407. https://doi.org/10.1093/zoolinnean/zlac010  

Birk MS, Ahmed-Begrich R, Tran S, Elsholz AKW, Frese CK and Charpentier E (2021) Time-Resolved Proteome Analysis of Listeria monocytogenes during Infection Reveals the Role of the AAA+ Chaperone ClpC for Host Cell Adaptation mSystems, 6(4), e00215-21. https://doi.org/10.1128/mSystems.00215-21  

Hüsing S, Halte M, Van Look U, Guse A, Gálvez EJC, Charpentier E, Blair DF, Erhardt M and Renault TT (2021) Control of membrane barrier during bacterial type-III protein secretion Nat Commun, 12(1), 3999. https://doi.org/10.1038/s41467-021-24226-1  

Bratovič M, Fonfara I, Chylinski K, Gálvez EJC, Sullivan TJ, Boerno S, Timmermann B, Boettcher M and Charpentier E (2020) Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches Nat Chem Biol, 16(5), 587–595. https://doi.org/10.1038/s41589-020-0490-4  

Broglia L, Lécrivain A-L, Renault TT, Hahnke K, Ahmed-Begrich R, Le Rhun A and Charpentier E(2020) An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y Nat Commun, 11(1), 1587. https://doi.org/10.1038/s41467-020-15387-6  

Gálvez EJC, Iljazovic A, Amend L, Lesker TR, Renault T, Thiemann S, Hao L, Roy U, Gronow A, Charpentier E and Strowig T (2020) Distinct Polysaccharide Utilization Determines Interspecies Competition between Intestinal Prevotella spp. Cell Host & Microbe, 28(6), 838-852.e6. https://doi.org/10.1016/j.chom.2020.09.012  

Lécrivain A-L, Le Rhun A, Renault TT, Ahmed-Begrich R, Hahnke K and Charpentier E (2018) In vivo 3′-to-5′ exoribonuclease targetomes of Streptococcus pyogenes Proc. Natl. Acad. Sci. U.S.A., 115(46), 11814–11819. https://doi.org/10.1073/pnas.1809663115